Biochemistry

NA

Presentation of concepts and case studies. Resolution of quizzes. Preparation of essays
and one oral presentation.

Students should be able to:
1) Interpret the representation of nuclides, indicate the electronic distribution of atoms,
describe the chemical bond and represent the structure of molecules;
2) Identify functional groups and other characteristic structures of molecules, isomers
and characteristic reactions of organic compounds; – Assign names to organic
compounds; Classify biomolecules and justify this classification;
3) Describe the metabolic processes for obtaining energy and classify organisms
according to their processes for obtaining energy and their carbon source;
4) Describe the cell structure and identify organelles and other cell components;
5) Explain the functioning of the genetic code, distinguish the structure of prokaryotic
and eukaryotic chromosomes, and enumerate and describe the phases of the processes
of DNA replication, transcription and translation;
6) Distinguish the types of cellular signal and explain the functioning of cellular
communication, namely nerve cells.

1 – Atomic Chemistry
Constitution of atoms
Electronic distribution of atoms
Atomica orbitals and molecular orbitals
Chemical bond: Covalent, ionic and metallic bonds
2 – Organic Chemistry
Families of organic compounds: Nomenclature of organic compounds; Functional
groups; Isomers; Main reactions; Reactions for the dentification of organic compounds
Biomolecules: Glucides; Lipids; Proteins; Nucleic acids
3 – Metabolism
Adenosine triphosphate (ATP) and bioenergetics
Metabolism of Carbohydrates, Lipids and Proteins
4 – Cell Biology
The cell as the basic unit of living things
Cellular organization
Cell Membrane, membrane transport and ion balance
Endomembrane System and Protein Synthesis
Mitochondria and energy production
Constituents of the nervous cells
5 – Introduction to Molecular Biology
The nucleous
DNA: perpetuation of genetic material
DNA and RNA – flow of genetic information: central dogma of molecular biology.
RNA and Proteins
6 – Cell Signaling

• - 1st Test: 32.5%; 2nd Test: 32.5%; Bibliographic essay: 20%; Bibliographic essay presentation and discussion: 15%. - 100.0%

• - Theoretical-Practical Exam: 80%; Practical Exam: 20%. - 100.0%

NAO

– Azevedo, C. (2012). Biologia celular e molecular (5.ª ed.). Lidel Edições Técnicas.
– Goldsby, K. & Chang, R. (2013). Química (11.ª ed). McGraw-Hill.
– Ferreira, W.F.C., de Sousa, J.C.F., Lima, N. (2010). Microbiologia. Lidel Edições Técnicas.
– Willey, J., Sandman, K. & Wood. D. (2022). Prescott’s Microbiology (12.ª. ed). Mc-Graw Hill.
– Quintas, A., Freire, A.P., Halpern, M.J. (2014). Bioquímica – Organização Molecular da Vida. Lidel Edições Técnicas.
– Voet, D., Voet, J. G., Pratt, C. W. (2018). Voet’s Principles of Biochemistry (5.ª ed.). Wiley.
– Laires, M.J. (2010) Bioquímica (4.ª ed.). Faculdade de Motricidade Humana