Base Knowledge
Mathematics A (12th year); Physics and Chemistry (11th year)
Teaching Methodologies
2 hours of theoretical classes per week, where the professor exposes the discipline contents, while applying the physical concepts in relevant exemples.
1 theoretic-practical class of 1 hour per week, where students proceed to the discussed resolution of exercises of practical application formulated with the aim of clarifying and relate the subjects discussed in the theoretical component, with application to the specificity of biomedical sciences.
Learning Results
• Deep know-how on the expression of physical quantities, in different unit systems and with correct quantification
• Understanding of theoretical principles of Fluid Mechanics and its application in the biological systems
• Understanding of the transport in biomembranes phenomena and its application in biophysics and physiology
Skills:
• Use of advanced knowledge of biophysics in understanding the underlying mechanisms and technology involved biomedical sciences
Competences:
• Make individual decisions and in multidisciplinary environment in matters involving technical and scientific knowledge based on biophysics
• Develop the ability to deepen and expand knowledge in biophysics.
Program
1 Units and systems. Numerical expression and uncertainties.
2 Fluid Mechanics
Hydrostatics: fundamental law; Archimedes ‘ principle
Hydrodynamics: equation of continuity and flow; Bernoulli equation; Viscosity; Poiseuille’s law; hydrodynamic
resistance; outflow regime.
Surfaces: surface tension; Laplace’s law; capillarity and Jurin’s law
Circulatory mechanics: cut voltage, speed profile and properties of blood vessels; equilibrium radius and complacency
2 Biomembranes
Dissemination: current density of solute; Fick’s laws; permeability; osmotic pressure; Kedem-Katchasky equation ; chemical potential
Ionic diffusion and bioelectricity: ion current density; Nernst-Planck and Nernst equation; electrochemica potential; Goldman-Hodgkin-Katz equation; resting and action potential.
Curricular Unit Teachers
Internship(s)
NAO
Bibliography
PRIMARY:
PEDROSO DE LIMA, Biofísica Médica (capítulos I e IV)
Editora: Imprensa da Universidade de Coimbra, 2002
TIPLER e MOSCA, Física para Cientistas e Engenheiros (capítulos 1 e 13)
Editora: LTC – Livros Técnicos e Científicos Editora Lda (2006)