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Sleep Pathology

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Base Knowledge

Fundamentals of Neuroanatomy and Neurophysiology.

Pathophysiology of neurological diseases.

Teaching Methodologies

The methodology adopted is expository, collaborative and active, using slides, videos and texts, which will be made available to students.

Learning Results

The student must acquire knowledge of :

* Detailed anatomy of the regulatory structures of the circadian cycle of sleep.

* Neurophisiologic and cellular mechanisms underlying sleep.

* Pathophysiology and treatment of sleep disorders.

 

The student must acquire skills and competences:

* Recognize of patological circadian cycle of sleep.

* Evaluate and correlate clnico-anatomically in the approach to clinical cases.

* Discuss the different pathologies of sleep, their etiopathogenies and differential diagnosis, clinical manifestations and treatment.

* Analyze and classify the different polygraphic sleep studies, recognizing their criteria and usefulness in the approach to patients with suspected sleep pathology.

* Integrate the evaluation methods of sleep and its conclusions in the clinical context, complementing the objective and specificity of each of them in the different pathologies of sleep.

Program

– Physiology and neurophysiological mechanisms that generate sleep: circadian cycle.
– Hypersomnia: definition and differential diagnosis.
– Sleep disturbances associated with respiratory diseases: upper airway resistance syndrome, nocturnal bronchial asthma, chronic obstructive pulmonary disease, alveolar hypoventilation syndromes.
– Sleep disorders associated with neurological and psychiatric diseases: dementia, Parkinson’s disease, epilepsy, horse headaches, depressive syndrome, among others.
– Anxious disorders, panic disorders, psychoses, alcoholism and its impact on sleep.
– Restless legs syndrome and periodic sleep movements: classification and differential diagnosis with other involuntary movements.
– Particularities and characterization of sleep in pediatric age.
– Obstructive Sleep Apnea Syndrome (OSAS) in adults and children: pathophysiology, risk factors, clinical manifestations and complications.

Curricular Unit Teachers

Paulo José Simões Carvalho de Paiva Coelho

Internship(s)

NAO

Bibliography

PRIMARY:

– Stephen H. Sheldon, Richard Ferber e Meir H. Kryger. Principles and Practice of Pediatric Sleep Medicine.  Elsevier Saunders, USA, 2005.

– Douglas B. Kirsch. Sleep Medicine in Neurology. Chichester, West Sussex, UK: Wiley Blackwell, 2014

– Meir H. Kryger, Thomas Roth, William C. Dement. Principles and practice of sleep medicine. Philadelphia: Elsevier Saunders, USA, 2005.

– Antonio Culebras. Case Studies in Sleep Neurology: common and uncommon presentations. Cambridge University Press, UK, 2010.

– Meir H. Kryger. Atlas of clinical sleep medicine. Philadelphia: Elsevier Saunders, USA, 2010.

– Nic Butkov, Teofilo Lee-Chiong. Fundamentals of sleep technology. Philadelphia: Wolters Kluwer, USA, 2007,

 

SECONDARY:

– Berry RB, Quan SF, Abreu AR, et al.; for the American Academy of Sleep Medicine. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Version 2.6. Darien, IL: American Academy of Sleep Medicine; 2020.

– The American Academy of Sleep Medicine International Classification of Sleep Disorders, Revised – Diagnostic and Coding Manual,  3rd edition (ICSD -3), 2014.