Immunology

Base Knowledge

– Anatomy and Physiology
– Basic Microbiology

Teaching Methodologies

The learning process is supported with 1) Theoretical classes, suported with videos and “power point” presentations. In these classes the student will present and comment articles from diferent themes, allowing to the teacher assess the student’s knowledge. 2) Laboratory practical classes with technical execution and field lessons in ESAC animal production units, for sampling blood and faeces in mammals and poultry; 3) Tutoriadas classes where students have the teacher’s participation in the preparation of papers and research.

Learning Results

The aim of this course is to obtain skills into basic Immunology and into their technological aplications for the animal diseases diagnosis, immunization and other technological aplications, promoting in the student the analysis capacity, protocols execution and knowladge objectivation in result of the teorethical and pratical courses. The students must achieve the following learning outcomes:
Skills: To understand the fundamentals of Immunology-1. Describe the components of the immune system and their functions; 2. Explain the mechanisms of cellular interaction in non-specific and specific responses; 3. Run immunological techniques. 4. Acquire ability to explain the basics of the immune-based techniques.

Program

Module1: The components of the immune system
1) Infectious agents and antigenic determinants; 2) Primary and secondary lymphoid organs; 3) innate immunity: barriers and non-specific immune response mechanisms-the inflammatory process and cells of phagocytosis, concept of opsonins and receptors, complement, cytokines. NK, dendritic cells 4) major histocompatibility complex (MHC) and histocompatibility molecules; 5) T cells and B cells; 6) Immunoglobulins and cytokines.
Module 2: Immunological response:
7) Mechanisms of antigens processing and presentation – cells and mechanisms; 8) cellular and humoral response; 8) mucosal protection; 9) transfer of immunity; 10) vaccines and vaccination; 11) primary and secondary response.
PRACTICAL CLASSES: 1)sampling from alive animals (bood and feces); 2) immunological techniques: agglutination, ELISA and indirect immunofluorescence, immunobloting.

Curricular Unit Teachers

Grading Methods

FREQUÊNCIA
  • - APRESENTAÇÃO DE TRABALHOS (N=3) - 20.0%
  • - TESTES (N=4) - 80.0%

Internship(s)

NAO

Bibliography

AROSA, F., CARDOSO, E.M., PACHECO, FC. Fundamentos de Imunologia. LIDEL, 2007. ISBN 978-972-757-396-7.

Artigos vários:
Immunobiology ISSN: 0171-2985
Microbes and Infection ISSN: 1286-4579
Veterinary Immunology and Immunopatology
Veterinary Parasitology ISSN: 0304-4017.

Current Protocols in Immunology (Wiley, 2018). [E-Reader Version]. Online ISBN: 9780471142737. DOI: 10.1002/0471142735. Retrieved from https://currentprotocols.onlinelibrary.wiley.com/loi/1934368. Artigos de revistas (entre outras)

Gerald N. Callahan, Robin M. Yates (2014). Basic Veterinary Immunology. University Press of Colorado, p.337. ISBN 1607322188, 9781607322184.

TIZARD, Ian R. Veterinary immunology: an introduction. 6th ed. Philadelphia: W. C. Saunders Company, Cop. 2000. ISBN 0-7216-8218-9.

Yuan, S., Tao, X, Huang, S., Chen,S., Xu, A. (2014). Comparative Immune Systems in Animals. Annual Review of Animal Biosciences. Vol. 2:235-258. https://doi.org/10.1146/annurev-animal-031412-103634