Technology and Galenic Pharmacy II

Teaching Methodologies

T and TP lectures using audiovisual and interactive means between students and teacher.Demonstrative and active practical classes with interpretation and execution of some techniques that lead to the preparation,packaging and labeling of medicines. Application of some control procedures for the prepared dosage forms.
Continuous assessment with the completion of frequency to the T component and TP assessment through the
preparation and presentation, in poster form, of a bibliographic research work. Continuous assessment of the PL component, taking into account the attendance to classes and the interest and motivation of the student throughout the semester, and through an assessment with the execution of a pharmaceutical form and its final report. In all assessments, the student must have a minimum score of 9.5. Theoretical part 50%, theoretical-practical 10% and practical 40%. The final grade is obtained by the weighted average of the three corresponding matrices

Learning Results

At the end, students must master the terminology, concepts and technical-scientific aspects inherent to medicines and pharmaceutical technology of dosage forms. It is intended to enable the student with fundamental knowledge about the pharmaceutical forms addressed in relation to the operations to which the substances are subjected, the properties of the products used, the composition, application and preparation procedures and quality control. In the practical component, the student must be able to autonomously apply rational and scientific methods for the formulation and preparation of dosage forms, to interpret the formula, to know how to associate the substances, the incompatibilities that may arise and the fundamental aspects of labeling , conservation and storage of the prepared formulas. Know the main pharmaceutical forms suitable for modifying the release of drugs and their important therapeutic and/or diagnostic applications.

Program

Pharmaceutical forms obtained by molecular dispersion: solutions and syrups. Pharmaceutical forms obtained by dissolution and evaporation: extracts. Pharmaceutical Forms obtained by complex or multiple operations: for application to the skin (ointments, creams, pastes, gels or ointments-jelly, liniments, lotions, soaps, plasters and transdermal preparations), for auricular use, for rectal application (suppositories, enemas) , for vaginal application (eggs, vaginal tablets), for ophthalmic use (ophthalmic ointments, eye drops), for nasal use, for urethral use and for parenteral use (injectable preparations). Pharmaceutical operations, production technologies, laboratory and industrial equipment, biopharmaceutical aspects, stability and quality control. Excipients. Labelling, packaging and storage conditions. Controlled release pharmaceutical forms: concepts, requirements and advantages. Liposomes, nanoparticles, microencapsulation, micelles and microemulsions.

Curricular Unit Teachers

António Jorge Dias Balteiro

Internship(s)

NAO

Bibliography

Farmacopeia Portuguesa IX. INFARMED. 2009
Tecnologia farmacêutica – L. N. Prista, A. C. Alves, R. M. R. Morgado, vol. I, II, III – Fundação Calouste Gulbenkian
Formulário Galénico Português. ANF. 2005.
Handbook of Pharmaceutical Excipients. RC Rowe, PJ Sheskey and SC Owen (Eds.), Pharmaceutical Press, London,
2006.
Remington – A Ciência e a Prática da Farmácia. Alfonso R. Gennaro. 20ª Edição.
Guia Prático da Farmácia Magistral: Farmacotécnia, Boas práticas de manipulação, Controle de Qualidade, Aspectos
Biofarmacêuticos, Excipientes e veículos, Procedimentos operacionais padrão. Anderson de Oliveira Ferreira, 2ª
Edição, Pharmabooks
Teoria e Prática na Indústria Farmacêutica. I e II Volume. Serviço de Educação e Bolsas. Fundação Calouste
Gulbenkian. Leon Lachman; Herbert A. Lieberman; Joseph L. Kanig
Martindale – The Complete Drug Reference”. 37ª Edição. Pharmaceutical Press, 2011.
Jain K: The Handbook of Nanomedicine: Humana Press; 2012.