Teaching Methodologies
Teaching combines theoretical, theoretical-practical, and laboratory classes, promoting the integration of knowledge, application, and reflection.
- Theoretical Classes: content is presented with examples and case studies, using active learning methodologies that encourage student participation and guided research.
- Theoretical-Practical Classes: students solve exercises and problems individually or collaboratively under the instructor’s guidance, applying concepts and developing analytical skills.
- Laboratory Practical Classes: involve the reading, planning, execution, and critical analysis of experimental work, culminating in the preparation of scientific article-style reports and the creation and presentation of a poster.
These methodologies foster autonomous, collaborative, and student-centered learning, in alignment with the pedagogical model of the program.
Learning Results
At the end of the course, students will be able to:
- Identify the role of the bioreactor as a central element of a bioprocess and differentiate the bioproducts obtained.
- Apply terminology, kinetic models, and stoichiometric/kinetic parameters in practical bioprocess contexts.
- Select the most appropriate type of bioreactor, operating mode, and process conditions, and perform quantitative evaluations of biomass, substrate, and product evolution.
- Analyze mixing and oxygen transfer mechanisms in bioreactors and evaluate their impact on process performance.
- Solve applied problems related to stoichiometry, kinetics, mass balances, and bioreactor modelling.
- Prepare scientific reports and communicate results effectively in both scientific paper and poster formats.
- Reflect critically on the limitations of acquired concepts and acknowledge the need for continuous learning.
Program
-
A Theoretical-Practical Component
- Stoichiometry and kinetics of microbial growth, product formation and substrate consumption.
- Determination of kinetic parameters of microbial growth, process yields (biomass/product), and maintenance coefficients.
- Classification of bioreactors. Typical geometries and operating modes: batch, continuous, and fed-batch.
- Modelling of ideal bioreactors and prediction of the evolution of state variables. Mass balances.
- Mixing and stirring in bioreactors.
- Mass transfer applied to preliminary bioreactor design. Aeration in bioreactors.
- Bioprocess applications: case studies.
- Problem solving and application exercises.
B Practical Component
- Laboratory work on bioprocesses.
- Preparation of a scientific report in paper format.
- Presentation of results in scientific poster format.
Curricular Unit Teachers
Marta Helena Fernandes HenriquesInternship(s)
NAO
Bibliography
- BAILEY, JE – Biochemical Engineering Fundamentals. McGraw Hill, 1986.
- DORAN, PM – Bioprocess Engineering Principles. Elsevier, 1995.
- DUTTA, R – Fundamental of Biochemical Engineering. Springer, 2008.
- FONSECA, MM; TEIXEIRA, JA – Reactores Biológicos: Fundamentos e Aplicações. Lidel, 2007.
- LEE, J – Biochemical Engineering. Prentice-Hall, 2001.
- NAJAFPOUR, GD – Biochemical Engineering and Biotechnology. 3rd Ed. Elsevier, 2025.
- NAJAFPOUR, GD; HENDA, R – Principles of Chemical Engineering Processes: Material and Energy Balances. 3rd Ed. CRC Press, 2025.
- SHULER, ML; KARGI F – Bioprocess Engineering: Basic Processes. 3rd Ed. Prentice Hall, 2017.