Teaching Methodologies
Expository methodology with use of audio-visual media. There is also the independent study with research on the contents exposed. The knowledge assessment is made using a written test and presentation of a final paper. There is also a written examination of normal period, at the end of the semester and an appeal examination.
Learning Results
Know the structural and functional aspects of the cell macromolecules, as structural and functional unit of the body; understand the main biochemical reactions and enzyme kinetics of cell; understand the major metabolic ways and mechanisms of energy conversion.
Know, describe and interpret the main mechanisms that regulate the functioning of the organism.
Program
Organic components of the cell; Amino acids: acid-base properties; Protein; Enzymes and mechanisms of catalysis; Nucleic acids: DNA mutations and its implication in protein; Lipids; Carbohydrate; Isomerism of oses; Bioenergetics. Metabolism of cells; Metabolic ways (aerobic and anaerobic); Tricarboxylic acid cycle; Respiratory chain and oxidative phosphorylation; Respiratory chain inhibitors; Absorption, digestion and transport; Carbohydrate metabolism: Glycolysis; Gluconeogenesis; Pentose phosphate pathway; Glycogenolysis;
Glucogenesis; Lipids Metabolism; Biosynthesis of fat acids and triglycerides; Cholesterol metabolism; Biosynthesis of steroid hormones; Biosynthesis of bile acids; Protein Metabolism; Urea cycle; Integration of metabolism; Liver metabolism, brain, muscle and adipocytes; Metabolic adaptations: shor
Curricular Unit Teachers
Isabel Maria de Aguilar Cabral de Andrade RamalhoInternship(s)
NAO
Bibliography
Manuel Júdice Halpern. Bioquímica. 1997, Lidel Editora
Albert L. Lehninger. Princípios de Bioquímica. 2012, W. H. Freeman & Company
Trudy Mckee; James R. Mckee. Biochemistry: The molecular basis of life. 2008. Oxford
Jeremy M. Berg; John L. Tymoczko; Lurbert Stryer. Biochemistry. 2006. W. H. Freeman & Company
John Baynes; Marek H. Dominczak. Bioquímica Médica. 2011. Elsevier