Teaching Methodologies
Exhibition method using audiovisual media. It also includes the autonomous study with research on the exposed contents. The knowledge assessment is made through an individual test with a weight of 60%, a group work with a weight of 20%, a random evaluation taking place after presenting works with a weight of 15% and attendance and attendance with weight 5%, with a minimum score of 9 (nine) values at each time of assessment.
The approval in the discipline is obtained with a classification equal to or higher than 10 (ten) values, resulting from the weighted average of the classifications obtained in the various moments of evaluation.
The assessment can also be done with a written exam, with the same structure as the test, during the periods designated for the purpose.
Learning Results
Understand the concept of neoplasia as growth alteration and cell/tissue differentiation;
Recognize the geographical distribution and temporal evolution of the main types of human neoplasia; Identify the main phases of neoplastic development and the agents involved in this process;
Recognize the molecular/genetic bases underlying the process of tumorigenesis;
Recognize the process of tumorigenesis as an interaction between organism and environment;
Recognize and understand the main hereditary conditions associated with cancer;
Know the therapies used to treat cancer;
To know the main technical methods used in the diagnosis and laboratory monitoring in Oncobiology; Understand the basic mechanisms of therapy aimed at molecular targets;
Recognize the main fields and lines of research in Oncobiology.
Program
• Epidemiology;
• Biology of tumor growth;
• Molecular bases of cancer;
• Classification of tumors;
• Hallmarks of cancer;
Application of the different laboratory approaches for the diagnosis and monitoring of the contents mentioned below in cancer:
• Intercellular communication and signal transduction pathways;
• Cell proliferation and proteins that regulate cell proliferation;
• Angiogenesis;
• Apoptosis;
• Carcinogens;
• Phases of tumor growth;
• Invasion and Metastasis;
• Tumor stem cells;
• Tumor markers;
• Therapeutics: proteins as a therapeutic target;
• Resistance to therapy.
Curricular Unit Teachers
Fernando José Figueiredo Agostinho d' Abreu MendesInternship(s)
NAO
Bibliography
Referencia primaria
– DEVITA, Vincent T., Jr. ; LAWRENCE, Theodore S. ; ROSENBERG, Steven A., ed. lit. – Devita, Hellman, and Rosenberg’s cancer : principles & practice of oncology. 10th edition. Philadelphia, [etc.] : Wolters Kluwer, cop. 2015. xiv, 2234 p. ISBN 978-1-4511-9294-0
– ABELOFF, Martin D., ed. lit. – Abeloff’s clinical oncology. 4th ed. Philadelphia, PA : Churchill Livingstone/Elsevier, cop. 2008. xxx, 2555 p. ISBN 978-0-443-06694-8
– DAVIES, A. M. ; SUNDARAM, M. ; JAMES, S. L. J. ; ANDERSON-SEMBACH , S. ; BAERT, A. L., ed. lit. Imaging of bone tumors and tumor-like lesions : techniques and applications. Berlin ; Heidelberg : Springer, cop. 2009. XII, 698 p. ISBN 978-3-540-77982-7
– KOSS, Leopold G. ; ; MELAMED, Myron R., ed. lit. – Koss’ diagnostic cytology and its histopathologic bases. 5th ed. Philadelphia ; Baltimore : Lippincott Williams & Wilkins, cop. 2006. 2 vol. (xviii, 1752, 1-52 p.). ISBN 978-0-7817-1928-5.