Learning Results
– Know the main characteristics of viruses, classification, entry doors, routes of transmission, signs and symptoms
of a viral infection
– Know the transmissible viral liver diseases by transfusion and infection by retroviruses such as HIV and HTLV
– Understanding the key essential clinical and laboratory diagnosis of viral infections transmitted by transfusion
– To apply global knowledge of virology and know the major infectious complications of blood transfusion
– Run, validate and interpret the results of laboratory techniques and methods taught in screening, confirmation of
infection, and viral load quantification and monitoring of patients infected by viruses
– Tue-depth knowledge in their area of virology
– Learn other diseases transmitted by transfusion of blood components .
Have knowledge in the field of virology , which enable the laboratory to clinical practice
Program
Know the main ways to identify the laboratory level a viral infection, the detection of the virus or antigen this search
or antibodies produced by humans.
Infectious complications of blood transfusion
Infection by HAV, HBV, HCV, HDV, HEV, HGV, HIV 1 and HIV2 virus, HTLV I / II clinical manifestations, prevention,
chronic and asymptomatic carriers, routes of transmission.
Markers of active infection, risk factors, risk groups and risk, routes of transmission, serological and molecular
tests for the diagnosis of these viral infections, pre-testing routine blood donation, viral genome, surrogate
markers, viral load. Additional tests, Western Blot Tests mutations, epidemiology and vaccination.
Other viruses and infectious complications of transfusion
– Application of immunoenzymatic techniques in laboratory diagnosis of viral infections
– Confirmatory of the presence of anti-HCV and HIV Western blot
Internship(s)
NAO
Bibliography
1. Roitt I., Brostoff J., Male D. Imunologia; 5th Edition; Editora Manole LTD; São Paulo; 1999.
2. Murray P.R., Rosenthal K.S., Kobayashi, G.S., Microbiologia Médica; Guanabara Koogan 3ed 2000;
3. Thomas , H.C., Lemon,S., Zucherman,A.J. Viral hepatitis, Edition 3rd Blackwell, 2005
4. Mollison, P.L., Engelfreit, C.P., Contreras, M. Blood Trasnfusionj in Clinical Medicine; 11th Edition; Blackwell;2005
5. Brecher, M.E.:Technical Manual, 15th Edition, American Association of Blood Banks, 2005.
6. Quinley E. Immunohematology Principles & Practice, Lippincott William &Wilkins, 2011
7. Immunobiology of organ transplantation, David S. Wilker, Kluwer Academic 2004