Teaching Methodologies
Theoretical and theoretical-practical matrix (T and TP):
– Expository method leveraging student-teacher interaction through appropriate audiovisual and online platforms.
Student-centered teaching approaches through the analysis of articles, fostering knowledge application. Assessment is translated into 1 moment of written assessment combined with the presentation and discussion of a scientific article (15/20v).
Practical matrix (P):
– Learning is action-oriented through a laboratory component focusing extraction techniques, identification and chemical characterization of pharmacologically active compounds. Assessment occurs in 1 moment of practical assessment (5/20v).
Examinations according to academic calendars.
Learning Results
Upon completion of this course, students are expected to be able to:
– Identify the main groups of drugs of natural origin and the corresponding medicinal plants;
– Characterize extraction techniques as well as quantitative and qualitative methodologies employed in the analysis of bioactive compounds from medicinal plants;
– Understand the raw materials of natural origin commonly used in Pharmacy, as well as their analytical methodologies;
– Develop laboratory skills in the field of Pharmacognosy, understanding the multidisciplinary of phytochemical and pharmacological aspects.
Program
1. The pharmacognosy as a multidisciplinary science;
2. Phytochemical determinants, pharmacological&toxicological effects and monographic study of medicinal plants and/or raw materials enriched in:
I. Monosaccharides, polyholosides and polyuronides (e.g. honey)
II. Lipids (e.g. lanolin)
III. Aromatic compounds (e.g. essential oils)
IV. Alkaloids (e.g. Atropa belladonna L., Papaver somniferum L.)
V. Anthracene glycosides (e.g. Hypericum perforatum L.)
VI. Cardiotonic glycosides (e.g. Digitalis purpurea L.)
VII. Saponosides (e.g. Gingko biloba L.)
VIII. Polyphenolic compounds (e.g. Vaccinium corymbosum L.)
3. Extraction methods and qualitative/quantitative analysis:
I. Determination of reducing sugars
II. Determination of acidity, peroxide, iodine and saponification indices
III. General alkaloid reagents
IV. Borntraeger reaction
V. Characteristic reactions of cardiotonic glycosides
VI. • Determination of total phenolic content and antioxidant capacity
Internship(s)
NAO
Bibliography
COSTA, A. F., FARMACOGNOSIA, Vol. I, 5.ª edição, Fundação Calouste Gulbenkian, 2002
COSTA, A. F., FARMACOGNOSIA, Vol. II 5.ª edição, Fundação Calouste Gulbenkian, 2002
COSTA, A. F., FARMACOGNOSIA, Vol. III, 5.ª edição, Fundação Calouste Gulbenkian, 2002
Farmacopeia Portuguesa (Portuguese Pharmacopeia)