Biomateriais

The lectures are aimed at the presentation and development of materials that constitute thecore of the course. Lectures are following a script based on slides, frequent use of the backboard and dialogue with the students. In the problem solving classes, practical examples are presented aiming at an improved understanding of the lectures and the students are helped to solve them on their own. In some of the classes students present and discuss scientific articles which have previous been appointed to them. The final evaluation includes a “continuous” component which grades the presentation of the scientific articles plus the solution of a few other assignment. The final grade is obtained with 30% (6 points) for the above mentioned component and 70% (14 points) for the final exam.

The course introduces and critically analyses relevant aspects of biomaterials, with particular attention to their use in in the pharmaceutical and medical applications. These issues are focused on the mutual relations structure- property-application of biomaterials. Essentials aspects of synthesis, processing, characterization, properties, applications and biocompatibility interaction with biological systems, are also covered. It is intended to provide students with the tools to understand the multidisciplinarity involved in the development and the use of biomaterials and, at the same time, build skills to: –identify the various classes of biomaterials; –define biomedical applications according to the respective properties (e.g. drug delivery); –understand the importance of biomaterials in present and future applications; –read and understand scientific papers related to biomaterials.

Introduction to Biomaterials: definition; types; characteristics; materials used as such; historical perspective on the development and application of biomaterials.

Polymeric, ceramic, composite and metallic biomaterials. Biomedical devices for implantation in soft and hard tissues.

Physical, chemical, thermal and mechanical properties of the different biomaterials. Biodegradable materials. Hydrogels. Systems for controlled drug release.

Materials engineering and tissue regeneration.

Experts in biomaterials will be invited to present seminars on specific topics.

• - Exam - 75.0%
• - Oral presentation and research paper - 25.0%

NAO

• Park, Joon e Lakes,R.S.; – Biomaterials – An Introduction; Springer Science (2010). 3ª edição ISBN: 978-1-4419- 2281-6
•  Bhat, Sujata V.; – Biomaterials; Kluwer Academic Publishers (2002). ISBN: 0-7923-7058-9
• Dee, Kay C.; Puelo, David A.; Bizios, Rena – An Introduction to Tissue – Biomaterial Interactions; John Wiley & Sons (2002). ISBN 0-471-25394-4
• Ratner, B.D.; Hoffmann, A.S.; Schoen, J.E.; – Biomaterials Science: An Introduction to Materials in Medicine; Academic Press, Elsevier (2004) 2ª edição. ISBN: 978-0125824637
• Wong, Joyce Y.; Bronzino, Joseph D., – Biomaterials; CRC Press, Taylor & Francis Group (2007) ISBN-13: 978-0- 8493-788-1