Ecotoxicology

Basic knowledge of chemistry and biology

Presentation and debate of relevant theoretical-practical concepts in the classroom; Guidance on the autonomous
study of students by consulting the recommended bibliography; Discussion and reflection on relevant issues
related to the subject exposed in the classroom and presentation and discussion of case studies that reinforce
theoretical learning. Preparation of practical work that allows the consolidation of knowledge and learning in the
field.

THE STUDENT MUST ACQUIRE KNOWLEDGE OF:
Toxicology and ecosystems
Influence of Toxicology on the human environment
Influence of the toxicological effect on human health
THE STUDENT MUST ACQUIRE SKILLS TO:
Recognize and identify contamination factors
Recognize the possible effects of toxics on ecosystems
Routes of entry and distribution in the body
THE STUDENT MUST ACQUIRE COMPETENCES TO:
Develop identification and toxicological control plansDevelop plans for Mitigation, control and toxicological reduction
Control and combat toxicological effects on Human Health

Introduction to Environmental Toxicology and Ecotoxicology
Concepts in Toxicology and Human Health
Contamination and Pollution
– Emerging problems
– Current challenges
Characterization, distribution and movement of environmental toxics
Toxicological indicators, bioindicators and sentinel species
Dose-response relationship
Exposure to toxics
– Absorption pathways
– Distribution
– Detoxic metabolism and excretion
Dynamic drug: general mechanisms of action, target organs
Non-target organ toxicity
Factors Affecting Toxicity
Bioaccumulation and biomagnification
Main classes of environmental toxic agents and their mechanisms of action
– Metals
– Organic compounds: Pesticides, Dioxins, Polychlorinated Biphenyls, Polycyclic Aromatic Hydrocarbons
– Endocrine disruptors
– Organic solvents
– Others
Environmental contamination biomarkers
– Exposure
– Effects
– Susceptibility
Ecotoxicity assessment methods and Risk assessment
Nanotechnology and health effects

NAO

Primary Bibliography

ASANTE-DUAH, Kofi – Risk assessment in environmental management: a guide for managing chemical contamination problems. Chichester; New York; Weinheim [etc.]: John Wiley & Sons, 1998. XIX, 515 p. ISBN 978-0-471-98147-8.

CRAVEIRO, João Lutas; SILVA, Paula Antão da – Environment, science and utopia for sustainable development?. Lisbon: LNEC, 2000. III, 15 p. ISBN 972-49-1843-2.IZRAEL, Yu. A. – Ecology and control of the natural environment. Dordrecht: Klumer Academic Publishers, 1992. X, 420 p. ISBN 0-79231197-3.

KIMBROUGH, Renate D. [et al.] – Clinical effects of environmental chemicals: a software approach to etiological diagnosis. New York: Hemisphere Publishing Corporation, 1989. X, 110 p. ISBN 0-89116-921-0.

Environmental contamination manual. Madrid: Mapfre, 1994. XIV, 578 p. ISBN 84-7100-957-9.

SEOANEZ CALVO, M. – Planning and control of environmental contamination. Madrid: Mapfre, [n.d.]. XIII, 590 p. ISBN 84-7100-148-9.

WABEKE, Roger L. – Air contaminants and industrial hygiene ventilation: a handbook of practical calculations, problems, and solutions. Mouth Raton; London: Lewis Publishers, 1998. [16], 219 p. ISBN 978-1-56670-307-9.

Secondary Bibliography

BORREGO, Carlos, ed. lit. – Investigação em ambiente e saúde [Brochura]: desafios e estratégias. Aveiro:
Universidade de Aveiro, 2009. 98 p. ISBN 978-972-789-288-4.
DUVIGNEAUD, Paul – A síntese ecológica. 2ª ed. rev. e corrigida. Lisboa: Instituto Piaget, D.L. 1996. XXXVI, 786 p.
ISBN 978-972-8245-43-2.
FERRAZ, Ana Isabel ; RODRIGUES, Ana Cristina – Biotecnologia : ambiente e desenvolvimento sustentável. [1ª ed.].
Porto : Publindústria, cop . 2011. xvii, 283, [3] p. ISBN 978-972-8953-81-2.
WALKER, C. H. [et al.] – Principles of ecotoxicology. 3rd ed. Boca Raton; London; New York: Taylor & Francis, 2006.
xxiii, 315 p. ISBN 978-0-8493-3635-5.
IZRAEL, Yu. A. – Ecology and control of the natural environmemt. Dordrecht: Klumer Academic Publishers, 1992. X,
420 p. ISBN 0-79231197-3.
Manual de contaminación ambiental. Madrid: Mapfre, 1994. XIV, 578 p. ISBN 84-7100-957-9.