Oncology I

Students must have previous knowledge on Cell Biology, Radiobiology and General Pathology.

During classes a theoretical exposure of the different topics will take place, encouraging an active participation of the students. Clinical problems will be discussed in a team-work fashion throughout the semester, in order to improve their clinical thinking and interpretation of imaging exams used for diagnosis, staging and follow up, as well as their ability to select the best treatment for each case.

The student must acquire:

– Knowledge on epidemiology, carcinogenesis, screening, semiotics, medical exames for diagnosis and staging, therapeutic approaches and prognosis for different malignant tumours, as well as knowledge on treatment intent (curative vs. palliative) and the importance on multidisciplinary group meetings. All topics will be addressed for different kinds of malignant neoplasias and will be adapted to each specific clinical situation.

– Aptitude to identify signs and symptoms related to specific oncologic diseases, recognising the best methods for diagnosis, staging and treatment.

– Competence on relating the natural history of a tumor to signs on medical imaging exams, as well as with the most adequate treatment for the patient, either uni- or multimodal.

General concepts in Oncology
– Hallmarks of cancer
– Molecular and cell biology in carcinogenesis
– Therapeutic targets in Oncology
– Microbiome and neoplasia
– Treatment strategies in Oncology: intent, uni- vs. multimodal treatment
– Clinical application of radiobiology principles
– Use and mechanism of action on the main drugs in Oncology
– Drug-radiation interaction in multimodal treatment
– General concepts in Clinical Oncology: epidemiology, semiology, diagnosis, staging, multidisciplinary treatment decisions, follow-up and side-effects
– Screening in Oncology
– Pathology in Oncology
– Imaging exams for diagnosis and staging
– Clinical trials in Oncology 

Specific clinical approach of malignant neoplasms:
– Breast
– Male reproductive system
– Female reproductive system
– Urinary tract

NAO

Primary:
– DeVita VT, Rosenberg AS, Lawrence TS. DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology. 12th Edition (2022), Wolters Kluwer. ISBN: 978-1-97-518474-2
– Halperin E, Wazer D, Perez C, Brady L. Perez & Brady’s Principles and Practice of Radiation Oncology. 7th edition (2018), Lippincott Williams & Wilkins (LWW). ISBN: 978-1-49-638679-3.
– Tepper JE, Foote RL, Michalski JM. Gunderson & Tepper’s Clinical Radiation Oncology. 5th edition (2020), Elsevier. ISBN: 978-0-32-367246-7.
– Hansen EK, Roach III M. Handbook of Evidence-Based Radiation Oncology. 3rd edition, Springer. ISBN: 978-3-319-62642-0.

Secondary:
– Amin MB, et al. (Eds.). AJCC Cancer Staging Manual. 8th edition (2017), Springer. ISBN: 978-3-319-40617-6.
– International Guidelines from National Comprehensive Cancer Network. Available in https://www.nccn.org
– International Guidelines from European Society for Medical Oncology. Available in https://www.esmo.org/guidelines
– Other relevant guidelines for diagnosis, staging and treatment in Oncology.
– Relevant publications in this scientific topic.