Base Knowledge
Students must know basic concepts on neuroanatomy, neurophysiology and general pathology.
Teaching Methodologies
The adopted methodology is actively expository using slides, videos and texts. Clinical cases based on the syllabus will be discussed during classes.
Learning Results
The student must acquire knowledge on:
– Anatomophysiology of regulatory regions of the circadian cycle of sleep.
– Neurological semiology.
– Neurophysiology and cellular mechanisms of sleep.
– Pathophysiology of central or peripheral neurological pathologies.
– Pathophysiology and treatment of sleep disorders.
– Identify common findings of neurological pathologies in complementary exams for diagnosis in neurology, discussing them and promoting the differential diagnosis.
The student must acquire skills and competences of:
– Interpret a clinical history of a patient with neurological pathology.
– Identify the most frequent neurological symptoms and more prevalent diseases.
– Recognise pathological changes of the circadian cycle of sleep.
– Recognise the topographical semiology of the lesions in the nervous system and the consequent understanding of the compromised functions.
– Discuss the different sleep disorders, their aetiology, differential diagnosis, clinical manifestations and treatment.
– Recognise the basic meaning of complementary diagnostic exam results.
– Analyse and classify the different polygraphic sleep studies, recognising their criteria and usefulness in the approach to patients with a suspicion of sleep disorders.
– Integrate the different methods of sleep evaluation in a clinical context, considering their goals and specificities.
– Understanding the role of fundamental research in the neurosciences.
Program
I. Neurological Pathology
Worldwide impact of the neurological diseases
Approach to the neurological patient: major signs and symptoms, specificities for the clinical history
Cerebrovascular diseases
Headache
Movement disorders
Cognitive deficit and dementias
Infections of the Nervous System
Multiple sclerosis and demyelinating diseases
Epilepsy and related diseases
Disturbances of consciousness
Neuro-Oncology
Neuro-Ophthalmology and Neuro-Otology
Cerebellar ataxias and related diseases
Neuromuscular disorders
Autonomic and metabolic dysfunction
II. Sleep Pathology
Physiology and neurophysiological mechanisms that generate sleep
Hypersomnia
Sleep disorders associated with respiratory diseases
Sleep disorders associated with neurological and psychiatric diseases
Anxiety, panic disorders, psychoses, alcoholism and their impact on sleep
Restless legs syndrome and periodic sleep movements
Specifications and characterisation of sleep in paediatrics
Obstructive Sleep Apnea Syndrome (OSAS) in adults and children
Curricular Unit Teachers
Internship(s)
NAO
Bibliography
Primary:
– Ropper A, Samuels M, Klein J, Prasad S. (2023). Adams and Victor’s Principles of Neurology, 12th Edition, McGraw-Hill Education & Medic, USA.
– Ferro José, Pimentel José (2013). Neurologia Fundamental – Principios, Diagnóstico e Tratamento. Lidel
– Stephen H. Sheldon, Richard Ferber e Meir H. Kryger. Principles and Practice of Pediatric Sleep Medicine. Elsevier Saunders, USA, 2005.
– Douglas B. Kirsch. Sleep Medicine in Neurology. Chichester, West Sussex, UK: Wiley Blackwell, 2014
– Meir H. Kryger, Thomas Roth, William C. Dement. Principles and practice of sleep medicine. Philadelphia: Elsevier Saunders, USA, 2005.
– Antonio Culebras. Case Studies in Sleep Neurology: common and uncommon presentations. Cambridge University Press, UK, 2010.
– Meir H. Kryger. Atlas of clinical sleep medicine. Philadelphia: Elsevier Saunders, USA, 2010.
– Nic Butkov, Teofilo Lee-Chiong. Fundamentals of sleep technology. Philadelphia: Wolters Kluwer, USA, 2007.
Secondary:
– Sá, Maria José (2014). Neurologia Clínica- Compreender as Doenças Neurológicas. Ed. Universidade Fernando Pessoa.
– Berry RB, Quan SF, Abreu AR, et al.; for the American Academy of Sleep Medicine. The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications. Version 2.6. Darien, IL: American Academy of Sleep Medicine; 2020.
– The American Academy of Sleep Medicine International Classification of Sleep Disorders, Revised – Diagnostic and Coding Manual, 3rd edition (ICSD -3), 2014.
– Relevant publications in this scientific topic.