Bioquímica

Biology and Chemistry.

Teaching methodologies: Presentation of concepts and case studies. Resolution of quizzes. Preparation of presentations, essays, reports, and quizzes.

This course aims to reflect the human being in its material dimension, common to all other living beings. Since all body structures consist of chemicals and since the functions of the organism result they all from chemical reactions, the knowledge of the composition and basic structure of the human being and what it shares with other living beings is essential for understanding of anatomy and physiology that characterize it. The study of cell function sets the framework of biochemistry in the most basic dimension of living beings and provides essential information to understand all the other studies that relate the human being in all domains of intervention, even in its psychosocial dimension.

I. Introduction
II – Atomic Chemistry
Constitution of atoms and molecules formation
Electronic distribution in the constituent atoms of organic matter Atomic
Orbitals and molecular orbitals
Electrons and chemical bonds
Ionic compounds
The carbon atom and the chemistry of life
III – Organic Chemistry
Families of organic compounds: Nomenclature of organic compounds; Functional groups; Isomers; Main reactions; Reactions for the dentification of organic compounds
Biomolecules, the matter of life: Proteins; Saccharides, Glucides or Carbohydrates; Lipids; Nucleic acids
IV – Metabolism
Adenosine triphosphate (ATP) and bioenergetics
Metabolism of Carbohydrates, Lipids and Proteins
V – Cell Biology
The cell as the basic unit of living things
Cellular organization
Cell Membrane, membrane transport and ion balance
Endomembrane System and Protein Synthesis
Mitochondria and energy production
Constituents of the nervous cells
VII – Introduction to Molecular Biology
The nucleous
DNA: perpetuation of genetic material
DNA and RNA – flow of genetic information: central dogma of molecular biology.
RNA and Proteins
VI – “Cell Signaling”

NAO

– Almeida, B. (2004). Fundamentos de Química Orgânica e Inorgânica. Edições Sílabo.
– Azevedo, C. (1999). Biologia celular e molecular (3th ed.). Lidel Edições Técnicas.
– Chang, R. (1994). Química (5th ed). McGraw-Hill.
– Ferreira, W.F.C., de Sousa, J.C.F., Lima, N. (2010). Microbiologia. Lidel Edições Técnicas.
– Mahan, B.H. (1993). Química um Curso Universitário (4th ed.). Addison-Wesley Iberoamericana, S.A..
– Prescott, L.M., Harley, J.P., Klein, D.A. (2004). Microbiology (6th ed). Mc-Graw Hill.
– Quintas, A., Freire, A.P., Halpern, M.J. (2008). Bioquímica-Organização Molecular da Vida. Lidel Edições Técnicas.
– Stansfield, W.D., Colomé, J.S., Cano, R.J. (1998). Biologia Molecular e Celular. McGraw Hill.
– Voet, D.J., Voet, J. G., Pratt, C. W. (2008). Principles of Biochemistry (3th ed.). Wiley.